Read Genomics Data Analysis: False Discovery Rates and Empirical Bayes Methods

Genomics Data Analysis: False Discovery Rates and Empirical Bayes Methods

David Bickel

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Description:Statisticians have met the need to test hundreds or thousands of genomics hypotheses simultaneously with novel empirical Bayes methods that combine advantages of traditional Bayesian and frequentist statistics. Techniques for estimating the local false discovery rate assign probabilities of differential gene expression, genetic association, etc. without requiring subjective prior distributions. This book brings these methods to scientists while keeping the mathematics at an elementary level. Readers will learn the fundamental concepts behind local false discovery rates, preparing them to analyze their own genomics data and to critically evaluate published genomics research.Key Features:* dice games and exercises, including one using interactive software, for teaching the concepts in the classroom* examples focusing on gene expression and on genetic association data and briefly covering metabolomics data and proteomics data* gradual introduction to the mathematical equations needed* how to choose between different methods of multiple hypothesis testing* how to convert the output of genomics hypothesis testing software to estimates of local false discovery rates* guidance through the minefield of current criticisms of p values* material on non-Bayesian prior p values and posterior p values not previously publishedWe have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Genomics Data Analysis: False Discovery Rates and Empirical Bayes Methods. To get started finding Genomics Data Analysis: False Discovery Rates and Empirical Bayes Methods, you are right to find our website which has a comprehensive collection of manuals listed.
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ISBN: 0367280361

Description: Statisticians have met the need to test hundreds or thousands of genomics hypotheses simultaneously with novel empirical Bayes methods that combine advantages of traditional Bayesian and frequentist statistics. Techniques for estimating the local false discovery rate assign probabilities of differential gene expression, genetic association, etc. without requiring subjective prior distributions. This book brings these methods to scientists while keeping the mathematics at an elementary level. Readers will learn the fundamental concepts behind local false discovery rates, preparing them to analyze their own genomics data and to critically evaluate published genomics research.Key Features:* dice games and exercises, including one using interactive software, for teaching the concepts in the classroom* examples focusing on gene expression and on genetic association data and briefly covering metabolomics data and proteomics data* gradual introduction to the mathematical equations needed* how to choose between different methods of multiple hypothesis testing* how to convert the output of genomics hypothesis testing software to estimates of local false discovery rates* guidance through the minefield of current criticisms of p values* material on non-Bayesian prior p values and posterior p values not previously publishedWe have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Genomics Data Analysis: False Discovery Rates and Empirical Bayes Methods. To get started finding Genomics Data Analysis: False Discovery Rates and Empirical Bayes Methods, you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.

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Genomics Data Analysis: False Discovery Rates and Empirical Bayes Methods

Genomics Data Analysis: False Discovery Rates and Empirical Bayes Methods

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