Read Scaffold Hopping in Medicinal Chemistry, Volume 58 (Methods and Principles in Medicinal Chemistry)

Scaffold Hopping in Medicinal Chemistry, Volume 58 (Methods and Principles in Medicinal Chemistry)

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Description:This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the reader's own projects.The first section serves as an introduction to the topic by describing the concept of scaffolds, their discovery, diversity and representation, and their importance for finding new chemical entities. The following parts contain a general description as well as case studies of the most common tools and methods for scaffold hopping, whether topological, shape-based or structure-based. The final part contains three fully documented real-world examples of successful drug development projects by scaffold hopping that illustrate the benefits of the approach for medicinal chemistry.While most of the case studies are taken from medicinal chemistry, chemical and structural biologists will also benefit greatly from the insights presented here.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Scaffold Hopping in Medicinal Chemistry, Volume 58 (Methods and Principles in Medicinal Chemistry). To get started finding Scaffold Hopping in Medicinal Chemistry, Volume 58 (Methods and Principles in Medicinal Chemistry), you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.

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ISBN: 3527665161

Description: This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the reader's own projects.The first section serves as an introduction to the topic by describing the concept of scaffolds, their discovery, diversity and representation, and their importance for finding new chemical entities. The following parts contain a general description as well as case studies of the most common tools and methods for scaffold hopping, whether topological, shape-based or structure-based. The final part contains three fully documented real-world examples of successful drug development projects by scaffold hopping that illustrate the benefits of the approach for medicinal chemistry.While most of the case studies are taken from medicinal chemistry, chemical and structural biologists will also benefit greatly from the insights presented here.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Scaffold Hopping in Medicinal Chemistry, Volume 58 (Methods and Principles in Medicinal Chemistry). To get started finding Scaffold Hopping in Medicinal Chemistry, Volume 58 (Methods and Principles in Medicinal Chemistry), you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.

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Scaffold Hopping in Medicinal Chemistry, Volume 58 (Methods and Principles in Medicinal Chemistry)

Scaffold Hopping in Medicinal Chemistry, Volume 58 (Methods and Principles in Medicinal Chemistry)

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